1. Minerals in everyday diet:

We do not manufacture them, so we need them for good work of our entire body system. We changed our Diet completely and we eat more cooked and processed food with less vitamins and minerals. Research review done by Royal Society of Chemistry in 1991 found that food in the UK since 1940 until 1991 have less mineral content (Ca, Mg, Fe, Cu & Zn) in range from 35 - 93 %. At the same time we changed the way of seeding the soil, changing natural mineral profile. Swede for example has had 110% increase of P, Phosphorus since 1940. (source: McCance and Widdowson (1991). The Composition of Foods, 5th Edition. Published by Royal Society of Chemistry/Ministry of Agriculture Fisheries and Food.) . 
 

2. Microbiota nad Probiotics:
Extensive use of antibiotics (from gr. anti=against  biota=life is "against life") was so overwhelming that now exist traces in environment as well in humans and animals. It becomes major cause for concern lowering its own efficacy and at the same time immunity in humans as well as in animals. Approx.2500 years ago Hippocrates have a theory that "all illnesses starts in our gut". When balance between different bio culture is disrupted we have less probiotic cultures and different organo-metal complexes in place. Long established Russian medical thought is that 1st brain is in stomach and 2nd brain is in head. At that time did not exist terms "pre-biotics" (food for probiotics) nor "pro-biotics" (which in gr. means "for life) but in many cultures in funny terms existed old saying that "you are what you eat". In last 20 years scientific evidence shows that almost 20% of our probiotics is removed or replaced by less friendly forms of organisms.